Project Lead, U.S. Commercial S-4 HANA - Vaccines

Company: Sanofi
Location: Morristown
Posted on: January 26, 2026

Job Description:

Job Title: Project Lead, U.S. Commercial S-4 HANA - Vaccines Location: Morristown, NJ About the Job Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. Collaborates cross-functionally with Vaccine Business Leaders across U.S. Customer Service, Trade, VaxServe, Reverse Logistics, and Operations (Mainline and Influenza) to proactively identify and resolve system and process challenges that impact product delivery to customers. Job Highlights: Leadership : Engage cross-functional/global teams and partner with vaccine stakeholders across the organization to drive alignment and support strategic initiatives. Modernization & Innovation Focus: Identify and deploy innovative system enhancements to streamline operations and maximize business efficiency. Adapt AI capabilities into solution delivery. Career Growth: Build deep expertise in vaccine business operations and project management to lead with confidence and deliver high-impact results. About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities: Business Impact Commercial Operations (ComOps)s Key User Support/Incident Management: Develop an internal network that can provide key commercial support and maintain ComOps relations with global solution and incident management teams. Identify system & process efficiencies for business, lead new requirements and development with global compliance, enablement & process owner teams. Lead Key User testing for business readiness, train Key Users & Leads on new functionality. Work with business leaders and Key Users to prioritize and execute ComOps incident processes, system change requests, and system enhancements. Drive global development and solution teams to implement timely corrective systems and process actions within agreed-upon SLAs to ensure uninterrupted commercial business. Ensure strict adherence and provide end-to-end oversight of SAP S/4 HANA commercial functions, achieving 100% compliance with regulatory and internal standards. Strategic Initiatives As a key contributor between the business and solution teams, identify cutting-edge system and process enhancements that streamline operations, elevate business performance, drive revenue, and maximize business efficiencies. Promote high-impact system strategies that improve upon customer and user experience, increase system automation while decreasing external support, and improve efficiency and task completion times for department processes. Develop deep expertise in the commercial vaccines business, processes, and systems to strengthen strategic decision-making and operational excellence. Scan external environments, biologics, and S/4 HANA users for innovations and process excellence. Identify and integrate AI capabilities into solution delivery. Co-develop and manage a ComOps User Access Management process. Maintain ComOps iShift User compliance, initiate global and local SAP training, provide system access, and manage user changes. People Leadership & Stakeholder Update Lead teams and maintain communication: Provide status updates through biweekly/monthly touchpoints with local business department leaders and Key Users across Customer Service, Trade, VaxServe, Reverse Logistics, Distribution, Customer Master Data, and Operations for system issues, fixes, and long-term business solutions. Initiate and lead war room meetings for S/4 vaccine crisis management. Work with the AMS crisis team to identify and engage with key business users and department leaders to quickly mitigate business risk and/or disruption of the U.S. vaccines business. Lead daily/weekly scrum calls with business partners, AMS, and solution members to drive on-time solution delivery. Proactively engage with global solution/AMS leadership when project timelines are in jeopardy of being missed and work through an agreed-upon contingency plan that supports commercial business needs. Collaborate with the business members on contingencies. Manage and own the timely engagement of a global, multi-functional, Flu Enablement Team to swiftly resolve system barriers impacting the distribution of the U.S. influenza vaccine. Partner with and conduct routine communication with Digital Delivery and Ecom teams for S/4-connected systems. Communicate and proactively engage with connected system teams during a S/4 crisis. Country launches/system upgrades: Alert commercial business partners of system outages and prepare business for scheduled downtimes and system upgrades. Lead post system restore testing by identifying critical tests, key team members, and overseeing completion for the testing team. Own post-test communications to business partners and commercial leaders. Location Specific: Morristown, NJ Support teams’ location base: Sanofi Trade: Morristown, NJ Customer Experience/Customer Service: Morristown, NJ Customer Master Data: Morristown, NJ Support teams’ User Access Management: Morristown, NJ About You Key Competencies: Strategic thinking and project management Leading teams and communication skills Problem-solving and decision-making Change management Stakeholder engagement Risk management Basic Qualifications: BS/BA required, preferably in Life Sciences, Technology, or Management and 5 years of relevant commercial vaccine or pharmaceutical experience 10 years SAP commercial experience, including S/4 HANA experience Formal or informal project management experience with the ability to lead and influence without authority Emotional intelligence and aptitude to work with multi-cultural teams in a highly matrixed environment Prior experience overseeing post-test communications to business partners and commercial leaders Aptitude and interest in learning and optimizing technical/ITS systems Travel requirements: Up to 20% domestic travel may be required Fine Print: This position description represents the major responsibilities and duties of the job but is not intended to be all-inclusive. The incumbent may be requested to perform job-related tasks beyond those specifically described in this description. Travel requirements: Up to 20% domestic travel may be required. Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. GD-SP LI-SP LI-Onsite vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Keywords: Sanofi, Hempstead , Project Lead, U.S. Commercial S-4 HANA - Vaccines, IT / Software / Systems , Morristown, New York